Metformin decreases miR-122, miR-223 and miR-29a in women with polycystic ovary syndrome
نویسندگان
چکیده
منابع مشابه
Metformin Therapy Decreases Hyperandrogenism and Ovarian Volume in Women with Polycystic Ovary Syndrome
Background: It is well known that there is a close relationship between elevated androgen plasma levels and the ultrasound findings of stromal hypertrophy in polycystic ovary syndrome (PCOS). The objective of this study was to investigate the effects metformin on the hyperandrogenism and ovarian volume in PCOS. Methods: The study is an unrandomized clinical trial with before–after desig...
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Abstract Background and Objective: Various cellular factors affect the process of HIV activity. One of these cellular factors are structures known as microRN that are expected to be involved in controlling HIV replication and infectivity. The expression of one or a set of them may represent the patient's clinical conditions. In this study, ...
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OBJECTIVE Preeclampsia is a pregnancy-associated disease with the impact of genetic, epigenetic and environmental factors. Increased apoptosis was observed in cells from preeclamptic placentas. MicroRNAs are involved in the regulation of apoptosis and are abundant in placenta. In this study, we focused on the analysis of differential gene expression of apoptosis-associated miRNAs in preeclampti...
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Background: Adequate nutritional status is a critical determinant of the onset and maintenance of normal reproductive function. More than 50% of women with PCOS are obese and central obesity plays a central role in the pathogenesis of PCOS by generating an insulin- resistant state, It has been proposed that recurrent hypoglycaemia due to hyperinsulinaemia could lead to decreased post-prandial s...
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Objective(s): MicroRNAs (miRs) are a class of small non-coding RNAs which are associated with tumor growth and progression. In the present study, we assessed the expression of selected miRs in malignant, benign, and adjacent normal breast tissues. Materials and Methods: The expression of miR-1297, miR-3191-5P, miR-4435, and miR-4465 were...
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ژورنال
عنوان ژورنال: Endocrine Connections
سال: 2020
ISSN: 2049-3614
DOI: 10.1530/ec-20-0195